Paget's disease: a family with six cases.
نویسندگان
چکیده
منابع مشابه
Giant cell tumours in mandible and spine: a rare complication of Paget's disease of bone.
The case of a man who was diagnosed as having polyostotic Paget's disease at the age of 52 years is described. He developed a rare neoplastic complication of Paget's disease--a giant cell tumour in his mandible, which was excised. Nine years after the diagnosis of this tumour he developed a new giant cell tumour arising from the L3 vertebral body. He was born in Avellino in Italy, from where fi...
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Palmoplantar keratodermas are a heterogenous group of diseases, one of them is Papillon-Lefevre Syndrome (PLS). This rare disease is inherited as autosomal recessive and characterized by focal hyperkeratotic plaques on elbows and knees, severe periodontal disease resulting in premature loss of teeth. We report two brothers with PLS who did not have a history of this disease in their famil...
متن کاملAngiogenesis in Paget's Disease of the Vulva and the Breast: Correlation with Microvessel Density
Our understanding of the pathogenesis of Paget's disease of the vulva and the breast remains limited. Current evidence supports the fact that angiogenesis plays an important role in the pathogenesis of several diseases. Therefore, we sought to define its role, as correlated with microvessel density, in Paget's disease of the vulva and the breast. Microvessels were analysed using anti-von Willeb...
متن کاملThe jaws and teeth in Paget's disease of bone.
That Paget's disease of bone may affect the jaws has been known since Moore's (1923) report of a case in which there was a bony tumour of the maxilla together with osteoporosis circumscripta of the frontal region, though until quite recently the disease in this site has been considered rare. Osteoporosis circumscripta itself has now been identified with an early phase of Paget's disease (Sosman...
متن کاملProtocol for stage 2 of the GaP study (genetic testing acceptability for Paget's disease of bone): A questionnaire study to investigate whether relatives of people with Paget's disease would accept genetic testing and preventive treatment if they were available
BACKGROUND Paget's disease of bone (PDB) disrupts normal bone architecture and causes pain, deformity, deafness, osteoarthritis, and fractures. Genetic factors play a role in PDB and genetic tests are now conducted for research purposes. It is thus timely to investigate the potential for a clinical programme of genetic testing and preventative treatment for people who have a family history of P...
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ورودعنوان ژورنال:
- British medical journal
دوره 4 5571 شماره
صفحات -
تاریخ انتشار 1967